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How can histoplasmosis be diagnosed?

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Histoplasmosis is usually diagnosed with a blood test or a urine test. Healthcare providers rely on your medical and travel history, symptoms, physical examinations, and laboratory tests to diagnose histoplasmosis.


What blood test is done for histoplasmosis?

Histoplasma complement fixation is a blood test that checks for infection from a fungus called Histoplasma capsulatum (H capsulatum), which causes the disease histoplasmosis.

Does histoplasmosis show up on xray?

After heavy exposure, radiographs may show widely disseminated, diffuse, fairly discrete nodular shadows throughout the lungs, with individual lesions measuring 1-10 mm in diameter. This form of disease is termed miliary histoplasmosis (see the image below); it is similar to miliary tuberculosis.

Can you see histoplasmosis on CT scan?

Background: Histoplasmosis pulmonary nodules often present in computed tomography (CT) imaging with characteristics suspicious for lung cancer. This presents a work-up decision issue for clinicians in regions where histoplasmosis is an endemic fungal infection, when a nodule suspicious for lung cancer is detected.

What is considered to be the gold standard for the diagnosis of histoplasmosis?

Isolation of H. capsulatum from clinical specimens remains the gold standard for the diagnosis of histoplasmosis.

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