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How do you confirm histoplasmosis?

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The most common way that healthcare providers test for histoplasmosis is by taking a blood sample or a urine sample and sending it to a laboratory. Healthcare providers may do imaging tests such as chest x-rays or CT scans of your lungs.


What is the gold standard for detecting histoplasmosis?

Isolation of H. capsulatum from clinical specimens remains the gold standard for the diagnosis of histoplasmosis.

What blood test is done for histoplasmosis?

Histoplasma complement fixation is a blood test that checks for infection from a fungus called Histoplasma capsulatum (H capsulatum), which causes the disease histoplasmosis.

Does histoplasmosis show up on xray?

After heavy exposure, radiographs may show widely disseminated, diffuse, fairly discrete nodular shadows throughout the lungs, with individual lesions measuring 1-10 mm in diameter. This form of disease is termed miliary histoplasmosis (see the image below); it is similar to miliary tuberculosis.

Can you see histoplasmosis on CT scan?

Background: Histoplasmosis pulmonary nodules often present in computed tomography (CT) imaging with characteristics suspicious for lung cancer. This presents a work-up decision issue for clinicians in regions where histoplasmosis is an endemic fungal infection, when a nodule suspicious for lung cancer is detected.

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