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How does botulism cause flaccid paralysis?

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Created: 2022-04-18 00:57:13

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The flaccid paralysis of botulism is the result of irreversible inhibition of acetylcholine (ACh) release at the presynaptic nerve terminal of the body's neuromuscular junctions (NMJs). 19 июл. 2021 г.


How does botulinum toxin lead to muscle paralysis?

Botulinum toxin works by blocking the release of acetylcholine from presynaptic motor neurons, and this chemical denervation causes a cascade of downstream events in the muscle thus causing muscle paralysis16.

Does botulism cause flaccid or spastic paralysis?

Botulism is a serious illness that causes flaccid paralysis of muscles. A neurotoxin, generically called botulinum toxin, causes botulism and the bacterium Clostridium botulinum (and rarely by C. butyricum and C. baratii) produces the neurotoxin.

Does botulism result in paralysis?

organisms. Botulism (“BOT-choo-liz-um”) is a rare but serious illness caused by a toxin that attacks the body's nerves and causes difficulty breathing, muscle paralysis, and even death. This toxin is made by Clostridium botulinum and sometimes Clostridium butyricum and Clostridium baratii bacteria.

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