Mirtazapine's Mechanism of Action The mechanism of action by which mirtazapine stimulates appetite is not fully described, but it likely involves antagonism of the 5HT2c receptor. This receptor is known for its appetite inhibition activity, as well as antagonism of the H1 receptor, which also helps regulate appetite.
How does mirtazapine increase appetite?
1 The most frequently reported side effects of mirtazapine are transient sedation and weight gain associated with an increased appetite, due to its effects on 5HT2C and histaminergic (H1) receptors.
How long does mirtazapine take to increase appetite?
On average, it takes about four weeks of taking Remeron daily before you start noticing an improvement in your appetite, sleep, and energy levels.
Is mirtazapine appetite stimulant?
Mirtazapine is an antidepressant approved for the treatment of major depressive disorder. It has been reported to also stimulate appetite and/or increase body weight, which may be beneficial in certain patient populations such as the elderly.
How much mirtazapine should I take for appetite?
Accordingly, individuals experiencing a loss of appetite may benefit from this side effect. The starting dosage of mirtazapine is typically 15 mg once daily, but there are instances, such as in seniors, when the starting dose of 7.5 mg is preferred.
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