It can happen when an adult takes several hundred thousand international units (IUs) of vitamin A. Chronic vitamin A poisoning may occur over time in adults who regularly take more than 25,000 IU a day. 26 янв. 2020 г.
How much vitamin A can cause toxicity?
Such megadoses can cause liver toxicity. Adults who consume > 4500 units (> 1500 RAE)/day of vitamin A may develop osteoporosis. Infants who are given excessive doses (18,000 to 60,000 units [6,000 to 20,000 RAE]/day) of water-miscible vitamin A may develop toxicity within a few weeks.
How much IU of vitamin A is toxic?
The acute toxic dose of vitamin A is 25,000 IU/kg, and the chronic toxic dose is 4000 IU/kg every day for 6-15 months. (Beta-carotene [ie, provitamin A] is converted to retinol but not rapidly enough for acute toxicity.)
What is an overdose of vitamin A?
Symptoms of Vitamin A Excess Most people with vitamin A toxicity have a headache and rash. Consuming too much vitamin A over a long period of time can cause coarse hair, partial loss of hair (including the eyebrows), cracked lips, and dry, rough skin.
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