Taking more than 10,000 mcg a day of oral vitamin A supplements long term can cause: Bone thinning. Liver damage. Headache.
How much vitamin A is poisonous?
The acute toxic dose of vitamin A is 25,000 IU/kg, and the chronic toxic dose is 4000 IU/kg every day for 6-15 months. (Beta-carotene [ie, provitamin A] is converted to retinol but not rapidly enough for acute toxicity.)
Can vitamin A be lethal?
Although it's extremely rare to die from a vitamin overdose, there have been reported instances of death related to vitamin toxicity. For example, hypervitaminosis A can be caused by taking one large dose of over 200 mg of vitamin A, or chronic use of more than 10 times the recommended daily intake ( 23 ).
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