Hepatotoxicity. Normal doses of vitamin A are not associated with liver injury or liver test abnormalities, but higher doses (generally more than 40,000 IU daily, ~12,000 μg) can be toxic. 4 нояб. 2020 г.
How much vitamin A can damage liver?
Taking more than 10,000 mcg a day of oral vitamin A supplements long term can cause: Bone thinning. Liver damage.
How much vitamin A is considered toxic?
The acute toxic dose of vitamin A is 25,000 IU/kg, and the chronic toxic dose is 4000 IU/kg every day for 6-15 months. (Beta-carotene [ie, provitamin A] is converted to retinol but not rapidly enough for acute toxicity.)
Can you get too much vitamin A from eating liver?
Vitamin A Toxicity It is possible, and even dangerous, to consume too much vitamin A. Eating large amounts of liver can lead to symptoms of vitamin A toxicity. Your own liver cannot process the excess vitamin A quickly enough, so eating a significant amount of liver regularly might lead to hypervitaminosis A.
How much vitamin A IU is toxic?
The daily biological need for vitamin A is estimated to be 800 retinol equivalents (RE)/d (2667 IU/d) for adult women and 1000 RE/d (3300 IU/d) for adult men; doses > or = 7500 RE (> or = 25000 IU)/d are considered potentially toxic over the long term.
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