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Is Benadryl safe for dogs to calm them down?

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One of the side effects of Benadryl is drowsiness, which helps to calm anxious dogs. The Merck Veterinary Manual states that diphenhydramine may relieve symptoms of mild-to-moderate anxiety in pets associated with travel. It also may help relieve motion sickness.


How long does it take Benadryl to calm a dog?

If using Benadryl as a mild sedative for motion sickness or any sort of thunderstorm or travel anxiety, it's best to think ahead so you can plan out when you give it to your doggo. It will usually take 30 minutes for Benadryl to take full effect, and you want your pup calm and anxious-free.

What can I give a dog to calm him down?

Your vet might recommend antidepressant medication for your pup that can greatly reduce their anxiety. Antidepressants — such as amitriptyline or fluoxetine (Prozac) — can be prescribed for dogs with severe anxiety. Sometimes vets will prescribe sedatives for dogs who experience situational anxiety.

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