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What does a drug that inactivates acetylcholinesterase do?

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Created: 2022-06-19 17:39:11

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Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic .


What happens when a drug inhibits acetylcholinesterase?

Cholinesterase inhibitor drugs, inhibiting AChE activity, maintain ACh level by decreasing its breakdown rate. Therefore, they boost cholinergic neurotransmission in forebrain regions and compensate for the loss of functioning brain cells.

What happens if acetylcholinesterase is inactivated?

Drugs that inactivate acetylcholinesterase and thereby prolong the presence of acetylcholine in the cleft can lead to repetitive firing of the muscle cell…

What is the function of an acetylcholinesterase inhibitor?

Cholinesterase inhibitors function to decrease the breakdown of acetylcholine. They SEe use in the treatment of Alzheimer and dementia symptoms.

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