Besides alcohol, cobalt, carbon monoxide, lead, cocaine and mercury, exogenous agents potentially inducing dilated cardiomyopathy could be drugs: the main pharmacological class known to induce such a serious adverse drug reaction (ADR) is anthracyclines [5, 6].
What are the 3 main causes of dilated cardiomyopathy?
Many different causes can lead to DCM, such as: Infections, such as HIV and Lyme disease. Autoimmune disease, such as polymyositis. Alcohol abuse, cocaine use, exposure to heavy metals, and certain chemotherapy drugs.
What is the most common toxin that causes chronic dilated cardiomyopathy?
Lead: Lead is a toxic heavy meatal whose excessive or chronic exposure can cause overt, clinical symptoms of cardiac and vascular damage with potential fatal consequences.
What is the most common cause of dilated cardiomyopathy?
Causes. The most common causes of dilated cardiomyopathy are: Heart disease caused by a narrowing or blockage in the coronary arteries. Poorly controlled high blood pressure.
How does drug use cause cardiomyopathy?
Cocaine decreases myocardial contraction. A lessening of coronary capacity and blood flow induces electrical irregularities in the heart, causing increased heart rate and blood pressure. Acute intoxication may cause nonischemic myocardial depression, leading to dilated cardiomyopathy.
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