If you take too much nitrous oxide you risk falling unconscious and/or suffocating from the lack of oxygen. People have died this way.
Can you overdose on nitrous oxide?
Despite the gas being safe and used medically, there's the risk of overdose. This can occur due to long-term exposure or from receiving too much of the gas. Signs of a possible overdose may include: irritation of the nose, eyes, and throat.
Does nitrous oxide damage lungs?
Inhaled nitric oxide also acts as a pulmonary irritant, causing priming of lung macrophages and oxidative damage to lung epithelial cells. Conversely, protective effects of nitric oxide have been described in a number of pathological states, including hyperoxic and ischemia/reperfusion injury.
How much nitrous oxide is toxic?
The ACGIH-recommended workplace exposure limit (TLV-TWA) is 50 ppm (90 mg/m3) as an 8-hour time-weighted average. Signs of acute toxicity are related to asphyxia and include headache, dizziness, confusion, syncope, seizures, and cardiac arrhythmias.
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