One study of patients who were hospitalized for histoplasmosis in the U.S. estimated the crude mortality rate to be approximately 5% for children and 8% for adults. Another study found a six-month mortality rate of 4% among patients with symptomatic histoplasmosis.
Can you survive with histoplasmosis?
Prognosis of Histoplasmosis Acute primary histoplasmosis almost always goes away without treatment. Chronic cavitary histoplasmosis can cause death. Untreated progressive disseminated histoplasmosis has a death rate of greater than 90%.
Can histoplasmosis be fatal?
Severe histoplasmosis Called disseminated histoplasmosis, it can affect nearly any part of your body, including your mouth, liver, central nervous system, skin and adrenal glands. If untreated, disseminated histoplasmosis is usually fatal.
What is the prognosis for histoplasmosis?
If untreated, subacute progressive disseminated histoplasmosis results in death within 2-24 months. A relapse rate of 50% is associated with acute progressive disseminated histoplasmosis, if treated. The rate decreases to 10-20% with life-long antifungal maintenance. Death is imminent without treatment.
Does histoplasmosis cause permanent lung damage?
Some people get better without treatment. An active infection will usually go away with antifungal medicine. But, the infection may leave scarring inside the lung. The death rate is higher for people with untreated disseminated histoplasmosis who have a weakened immune system.
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