Diphenhydramine (Benadryl) is an over-the-counter product well-tolerated by dogs and can have a mild sedative effect.
Is there an over-the-counter sedative for dogs?
While melatonin has proven beneficial in the management of certain endocrine disorders, it is a helpful adjunct in canine stress disorders. Therefore, melatonin is offered as an over-the-counter recommendation for the dog with hospital associated aggression and anxiety (Table 1).
What is the best medicine to calm a dog?
SSRIs and antidepressants are occasionally prescribed for dogs with anxiety, including fluoxetine and clomipramine.
More useful articles on a similar topic 👇
Will Benadryl calm a hyper dog?Can I give my dog 10 mg of Benadryl?