Fenbendazole should not be used in: puppies younger than 6 weeks of age.sick animals.
What are the side effects of fenbendazole in humans?
Fenbendazole binds beta-tubulin subunits of microtubules, interfering with their polymerization. Side effects include vomiting and diarrhea, although both are considered rare.
What happens when you take fenbendazole?
More than 50% of ingested fenbendazole is absorbed and metabolized in the liver, primarily to the active form, fenbendazole sulfoxide. Fenbendazole inhibits microtubule polymerization, and its efficacy as an anthelminthic results from its greater affinity for helminth tubulin than mammalian tubulin.
How much fenbendazole can a human take?
Fenbendazole seems to be well tolerated in humans after oral exposure (single oral dose up to 2,000 mg/per person; 500 mg/per person for 10 consecutive days); however observations in humans are limited. Fenbendazole is of low acute toxicity after oral exposure. No acute exposure limit is available.
Is fenbendazole toxic?
Fenbendazole, the active ingredient in Panacur and Safe-Guard, it is a benzimidazole dewormer which prevents cell division. It is generally considered a safe drug, toxicity only occurring at 100x overdoses and in exotic species. Fenbendazole isn't systemically absorbed and over 50% leaves the animal in feces.
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