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How long does it take for Benadryl to knock a dog out?

【Expert answer】
Any Q

Benadryl takes about 30 minutes to kick in.


How long does it take for Benadryl to sedate a dog?

If using Benadryl as a mild sedative for motion sickness or any sort of thunderstorm or travel anxiety, it's best to think ahead so you can plan out when you give it to your doggo. It will usually take 30 minutes for Benadryl to take full effect, and you want your pup calm and anxious-free.

How much Benadryl can I give my dog to sedate her?

The usual dosage is about 1 mg per pound, two to three times daily. Veterinarians often recommend that people start with a half dose to see how much it sedates the dog the first time.

Will Benadryl sedate a dog?

Benadryl has some efficacy in the prevention of motion sickness in dogs and as a mild sedative, but the effects are not the same as with people. Some dogs and cats can actually have the opposite reaction to Benadryl, causing hyperactivity instead of sedation.

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