The antidote for belladonna poisoning is Physostigmine, which is the same as for atropine 1. Physosigmine crosses the blood-brain barrier and reversibly inhibits anticholinesterase. Benzodiazepines are frequently used for sedation to control anticholinergic effects including delirium and agitation 2.
How is belladonna treated?
The treatment is mainly symptomatic including gastrointestinal decontamination with activated charcoal. In severe cases, physostigmine can be used as an antidote.
What happens if you ingest belladonna?
When taken by mouth: Belladonna is likely unsafe. It contains chemicals that can be poisonous even at low doses. Serious side effects might include blurred vision, fever, fast heartbeat, inability to urinate or sweat, hallucinations, spasms, mental problems, convulsions, coma, and others.
Can belladonna be fatal?
Belladonna, native to Europe and parts of Asia, can grow up to 5 feet. It has purple flowers and dark, inky berries that are slightly sweet. Belladonna's so toxic that eating a small quantity of its leaves or berries can be fatal to humans, particularly children, and some animals.
What does belladonna do to the brain?
Atropa belladonna (Deadly Nightshade) The alkaloids in Atropa can cross the blood–brain barrier to act on central cholinergic synapses, causing ataxia, disorientation, short-term memory loss, coma, and death.
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