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What dogs are predisposed to Fanconi syndrome?

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Fanconi syndrome has been reported in several different dog breeds, but the vast majority of reported cases (75%) have occurred in Basenjis. Approximately 10 – 30% of Basenjis in North America are affected.


What causes Fanconi like syndrome in dogs?

Acquired renal Fanconi syndrome is caused by several drugs such as gentamicin, tetracycline and azathioprine, exposure to toxins such as heavy metals, infections such as leptospirosis [6,7,8] and certain diseases such as primary hypoparathyroidism and copper associated hepatopathy [2, 5, 9].

How long can a dog live with Fanconi syndrome?

Median survival time after diagnosis of Fanconi syndrome was 5.25 years; median estimated lifespan was calculated to be between 11.3 and 12.1 years. Owners of 28 of 29 (97%) dogs still alive at the time of the study subjectively assessed their dogs' general condition as good to excellent.

Can Fanconi syndrome in dogs be cured?

Unfortunately, hereditary Fanconi syndrome has no cure. Even so, proper care can keep your dog's condition stable for years. Nutrition supplementation can prove crucial for dogs with Fanconi syndrome.

How is Fanconi syndrome inherited?

Fanconi anemia is most often inherited in an autosomal recessive pattern , which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.

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