The MSTN gene provides instructions for making a protein called myostatin, which is active in muscles used for movement (skeletal muscles) both before and after birth. This protein normally restrains muscle growth, ensuring that muscles do not grow too large. 1 дек. 2008 г.
What happens if you have no myostatin?
Lack of myostatin function results in the excessive growth of skeletal muscle, demonstrating the existence of a powerful mechanism to control muscle size in normal individuals (1).
Why is myostatin good?
In addition to its effect on skeletal muscle, myostatin has been demonstrated to play a significant role in the regulation of bone metabolism by suppressing bone formation [6] and stimulating bone resorption [7].