Botulism is a serious illness that affects the nervous system. It occurs when poisonous substances called botulinum toxins produce skeletal muscle paralysis. This paralysis can affect the muscles that help you move and breathe. Botulism is rare. 14 мая 2018 г.
What happens to the muscles in botulism?
Symptoms of botulism usually start with weakness of the muscles that control the eyes, face, mouth, and throat. This weakness may spread to the neck, arms, torso, and legs. Botulism also can weaken the muscles involved in breathing, which can lead to difficulty breathing and even death.
Does botulism affect smooth muscle?
At higher concentrations, botulinum toxin directly inhibits smooth muscle contractility as evidenced by the decreased contractile response to ACh.
What muscle group does botulism affect?
The typical neurologic presentation of botulism is a symmetric (same on both sides of the body), descending flaccid paralysis that begins in the nerves that control the muscles in the face, head, and neck (cranial nerves) and progresses to include proximal muscle groups such as hip and shoulder muscles and then distal ...
Does botulism cause muscles to contract?
Botulism invades nerve cells and interferes with the release of a substance called acetylcholine. The release of acetylcholine is necessary for muscles to contract. Botulism can eventually cause paralysis of the limbs, trunk, and respiratory system. As axons in the nerves are regenerated, paralysis will improve.
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