You shouldn't eat the eyes because they contain high amounts of glycoalkaloids, which can be toxic if consumed in large doses. Potatoes usually have glycoalkaloid compounds in them, but when unsprouted these remain at low levels.
What part of the potato is poisonous?
The nerve toxin is produced in the green part of the potato (the leaves, the stem, and any green spots on the skin).
Is it necessary to remove eyes from potatoes?
Do you need to remove the eyes? While most of the time the removal of the potato eyes is purely cosmetic, you should definitely remove the eyes if your potato has started to sprout in your pantry. Potatoes are a perennial from the nightshade family of plants, Solanaceae.