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Is botulism flaccid paralysis?

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Created: 2022-06-17 23:09:23

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Symptoms of foodborne botulism Foodborne botulism is characterized by descending, flaccid paralysis that can cause respiratory failure. Early symptoms include marked fatigue, weakness and vertigo, usually followed by blurred vision, dry mouth and difficulty in swallowing and speaking. 10 янв. 2018 г.


Is botulism ascending or descending paralysis?

The clinical syndrome of botulism is highly distinctive, consisting of symmetrical cranial nerve palsies, followed by symmetrical descending flaccid paralysis that may progress to respiratory arrest [19, 35].

Why botulinum toxin causes flaccid paralysis?

The flaccid paralysis of botulism is the result of irreversible inhibition of acetylcholine (ACh) release at the presynaptic nerve terminal of the body's neuromuscular junctions (NMJs).

Does botulism paralyze muscles?

Botulism is a rare but serious illness caused by toxins that produce skeletal muscle paralysis. This paralysis affects muscles that help you breathe and move.

What is flaccid paralysis How is it connected to botulism?

When the bacteria are in vivo, they induce flaccid paralysis. This happens because C. botulinum produces a toxin that blocks the release of acetylcholine. Botulism toxin blocks the exocytosis of presynaptic vesicles containing acetylcholine (ACh).

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